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10.1016/j.neuropharm.2019.03.010 35 LebourgeoisS.Gonzlez-MarinM

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Findings of synaptopathy in the auditory nerve center suggest that synapses degenerate during aging, and more so in non-type I a auditory nerve synapses, and may therefore play an important role in the development of ARHL [24]

It would be in a really small niche circuit, whereas now it is advertised and promoted, and companies are shouting about it, which I personally dont agree with

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Once ChREBP was bound to ChoRE, it was shown to activate multiple genes, notably those involved in fatty acid synthesis, such as ACC and FASN