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Description
The aims of this review are (1) to provide an overview of the clinical and biological overlap between neuropsychiatric long COVID and other fatigue-associated neuropsychiatric disorders, (2) to examine the shared molecular mechanisms of fatigue and depressive symptoms involving acetylcarnitine metabolism, and finally (3) to review the current evidence on acetylcarnitine supplementation studies as a treatment for fatigue-associated syndromes and pharmacological aspects of acetylcarnitine supplementation to provide a conceptual foundation for acetylcarnitine supplementation in neuropsychiatric long COVID syndrome
Ethics declarations Conflict of Interest Diego Maria Michele Fornasari received fees as congress speaker or consultant from the following pharmaceutical companies: Angelini, Abiogen, Alfasigma (the manufacturer of acetyl-l-carnitine), Chiesi, Istituto Gentili, Grunentahl, Molteni, Sandoz, SPA, Viatris, Zambon

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