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The kobs data as a function of inhibitor concentration from the GR (B) or TrxR assay (D) versus OPZ concentrations followed a polynomial equation (not shown), suggesting that more than one binding site of OPZ is involved in the presence of different enzyme species of reacted and unreacted enzymes in mixture during the course of the inactivation process

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Both GSNO concentrations (200 M and 500 M) significantly increased coronary flow during pre-ischemia compared to control

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Analogous to DNA methylation, a similar correlation has also been reported for the establishment of trimethylation at histone H4K3