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The affected enzymes, ERK1/2, along with their downstream targets, including c-Fos, c-Jun, and Egr-1, are believed to play significant roles in cell growth, migration, and angiogenesis, which is the development of new blood vessels

10.1002/jbt.23352 54 LeeH

I'm not medically trained but if someone has symptoms consistent with B12 deficiency and the symptoms improve/disappear with B12 injections/B12 supplements then it would suggest to me that the person needed B12

With a slower metabolic rate and thus slower nutrient absorption, you might book more frequent visits to foster more consistent nutrient delivery

Incorporating glycine through dietary sources or supplements could prove beneficial

The contribution of these metabolites was only detectable when cells were cultured under physiological conditions