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Similarly, nanocarrier systems, including polymeric nanoparticles, dendrimers, and lipidbased nanovesicles, offer the possibility of cellspecific targeting, for example, directing antiinflammatory or proregenerative agents toward activated macrophages, osteoclast precursors, or stem/progenitor cells involved in tissue repair
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Persistent senescent cells have been associated with aging or age-related diseases via secretion of proinflammatory cytokines that alter the tissue microenvironment or modify the function of normal cells (Baker et al., 2014)
PMID: 19230461 Kanfer I et al (1993): Pharmacokinetics of oral decongestants

Teschke, R