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Description
Discussing this option with your prescriber is worthwhile if dose escalation periods consistently produce palpitations or other significant symptoms

Most patients reach effective doses of 0.51.0 mg per week within 48 weeks, though some require higher maintenance doses
V.GueriguianJ

Nature Neuroscience, 20(5), 708716
, Reiner, D

The calculation process of and the list of drugs were described in Additional file 1: Table S2