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For long-term studies or to prevent degradation from repeated freeze-thaw cycles, it is best practice to aliquot the freshly reconstituted solution into single-use volumes and store them frozen at -20C or colder

Archived from the original on 6 April 2015

Despite the considerable progress for its clinical management, sepsis-related morbidity and mortality remain high (4), highlighting the importance of developing new strategies for sepsis prevention and treatment

The treatment combines fluids with electrolytes to manage dehydration

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Therefore, this will work only if one allele is sufficient for normal function