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As mentioned previously, there is generally a period of recovery between the lesion and the challenge and this delay may have introduced caveats since there is plasticity in the emetic reflex following nerve lesion, whereby the sensitivity of the animal is changed ( The vagus comprises A and B-fibres for visceral and motor input, but it is the C- fibers that carry afferent visceral input that have attracted the most attention (Wang et al., 2020)

A phase 2/3 study is to follow

10.1248/bpb.23.379 89 KimS.ParkS

In: Hayat S, Ahmad A, Alyemeni M (eds) Salicylic acid

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