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Reconstitution of TRAF3 in human multiple myeloma cell lines inhibited ChoK expression, suppressed the Kennedy pathway, and induced apoptosis, underscoring the role of elevated choline metabolism in sustaining the phenotype of TRAF3-deficient malignant B cells

Semin Oncol 12(2):160-79, 1985

Chronic SIRT1 supplementation in diabetic mice improves endothelial function by suppressing oxidative stress

These astrocytes secrete growth factors that mitigate secondary damage and promote tissue stabilization 174
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There are several major dopamine-related genes that may affect how many dopamine receptors a person has, which in turn can influence the overall activity of the brains dopamine system