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Thus, the action of LAC on BDNF levels and the rapid regulation of the glutamatergic system is in line with its antidepressant activity

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Peer review Peer review information Nature thanks Liang Ge, Jay Xiaojun Tan and the other, anonymous reviewers for their contribution to the peer review of this work

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369 Moreover, the attachment of electrophilic reagents directly to the reversible inhibitor scaffold enables the targeting of solvent-exposed cysteines located more than 10 from the binding site

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