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[DOI] [PMC free article] [PubMed] [Google Scholar] 242.Carmeliet P

Studies have found that berberine attenuates ischemia-reperfusion injury through NF-B nuclear translocation in mice with transient cerebral artery occlusion, however, this neuroprotective effect was more pronounced at the high dose (50 mg/kg) than the low dose (25 mg/kg) (Zhu et al., 2018)

[DOI] [PubMed] [Google Scholar] 66.Singh J, Giri S

Due to the role of vitamin C in redox reactions, most accepted health claims are related to protection against oxidative stress, the nervous system and collagen metabolism, and increasing iron absorption
Oxidative stress is often described as a self-propagating phenomenon on the basis of observations that when oxidative stressinduced excessive ROS release triggers cellular damage, damaged macromolecules themselves may behave as and/or become ROS
