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, Dohi E., Choi E

Once internalized, it is mandatory for the meningococcus to avoid lysosomal killing

Dysregulation or inappropriate activation of these signaling pathways can occur due to genetic mutations, infections, or other triggers, leading to an uncontrolled and amplified cytokine response

Sci Adv 9:eadf8582 Pitsawong W, Buosi V, Otten R, Agafonov RV, Zorba A, Kern N, Kutter S, Kern G, Padua RA, Meniche X et al (2018) Dynamics of human protein kinase Aurora A linked to drug selectivity

In a disease state, such as IBD, this apoptosis is greatly upregulated resulting in damage and increased permeability in the epithelial barrier and impairment of its basic functions

[DOI] [PMC free article] [PubMed] [Google Scholar] 87.Shalem O., Sanjana N.E., Zhang F