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Description
OSI-906 (linsitinib), a RTKI targeting both IGF-1R and IR, was investigated as a treatment for hormone sensitive breast cancer in combination with endocrine therapy and erlonitib in a phase II clinical trial (NCT01205685)

Further large-scale RCTs are required to confirm GSHs efficacy, determine optimal dosing, and assess long-term effects
Hosseinzadeh, A., Jafari, D., Kamarul, T., Bagheri, A
Single missed doses have minimal impact

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With single sessions ranging from $250 to $1,500, and loading dose packages potentially reaching $6,000, it requires thoughtful consideration
