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This is a general risk pattern whenever a treatment is unapproved, lacks strong human safety data, and is sourced outside regulated channels

The data is genuine

Even at extremely high doses of 5 mg, this interaction can easily be circumvented by taking biotin separately independent of meals or a vitamin B complex

Pancreatic and other digestive juices beyond the stomach can cause intestinal irritation and ulcers if patients smoke or take NSAIDs

However, MMA levels can be elevated in those with thyroid and kidney conditions, which limits the tests specificity (9, 10)
