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The formation of metal-flavonoid complexes significantly enhances their bioavailability, positioning these compounds as promising candidates for next-generation therapeutics ( Ehretia tinifolia extract (ETME) counteracts this response by activating the protective Nrf2/HO-1 pathway while suppressing NF-B/MAPK-mediated inflammation
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doi: 10.1016/j.biopha.2013.05.003 45 LiuYHLiYLShenHTChienPJSheuGTWangBYet al
doi: 10.3390/ijms23137267
