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Description
The practice is rooted in alternative medicine and was popularized in the 1920s and 1930s by the Gerson Therapy, which aimed to detoxify the body and promote healing through diet and coffee enemas

It can happen when high blood sugar damages nerves and the small blood vessels that supply them over time

The supplements delivery system may be a sublingual lozenge, a liquid, or a capsule or tablet that is meant to open up in the stomach or lower intestinal tract

Nov 2013;33(11):1184-90

Similarly, Zhang D et al

The MTHFR gene provides instructions for making this enzyme, which is necessary for the conversion of 5,10-methylenetetrahydrofolate (5,10-MTHF) to 5-methyltetrahydrofolate (5-MTHF)
