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New investigational drugs with single-agent activity in multiple myeloma
In humans, large vesicles of smooth endoplasmic reticulum are interspersed with small islets of small vesicles and densely packed tubules
Potentiating CD8+ T cell antitumor activity by inhibiting PCSK9 to promote LDLR-mediated TCR recycling and signaling
It is particularly useful for individuals who do not respond adequately to other management strategies, such as dietary modifications and pharmacotherapy [32,34]
