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In addition, IGF-1 is a neurotrophic factor that has also been suggested to be elevated in rodents maintained on a restricted diet regimen [178]
Chronic hypoxia promotes -syn phosphorylation at ser129 and abnormal aggregation in the mouse hippocampus Hyperphosphorylation and abnormal aggregation of -syn are closely related to neuronal degeneration
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10.1038/377532a0 [DOI] [PubMed] [Google Scholar] Mittal N., Tan M., Egbuta O., Desai N., Crawford C., Xie C