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Standard protocols use once-daily administration for 714 days during the induction phase, with some studies employing twice-daily dosing in the first week to maximize early receptor activation

[DOI] [PubMed] [Google Scholar] 27.Kikuchi E, Margulis V, Karakiewicz PI, Roscigno M, Mikami S, Lotan Y, et al

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As discussed in the previous section, numerous pharmacological inhibitors were also used for the study of GH and somatotrophs ( Figure 2 )