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Clin Mol Hepatol

Dihexa solutions were prepared by suspending dry stock dihexa in DMSO at 3 rag/niL and subsequent serial dilutions in 50% DMSO or HPLC grade water for the final the proteins present in the plasma samples were precipitated using three volumes of ice-cold acetonitrile

Here we use a derivative of DNQ, isobutyl-deoxynyboquinone (IB-DNQ) that is more potent and specific in killing TNBC cells than NQO1-activator -lapachone while displaying strong NQO1-dependence

It also has an antioxidant effect by stimulating the antioxidant enzyme superoxide dismutase and preventing the release of oxidation-promoting iron

High-quality supplements undergo strict quality control and safety testing

PMID: 42056497 Cell Metab 2021 Jan 5;33(1):110-127.e5