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Often in combination with corticosteroids, TMPSMX is also the drug of choice for treatment of PCP at high doses (1520 mg/kg/day divided every 68 h) due to superior efficacy, better tolerability, and/or ease of administration as compared to other treatment options such as atovaquone, dapsone plus trimethoprim, and clindamycin plus primaquine [16]

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Both studies achieved good results