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The results indicated that N-terminal modifications were particularly effective at enhancing metabolic stability, whereas C-terminal amidation offered more modest protection

Washington, DC: Taylor & Francis

He Y, Yue Y, Zheng X, Zhang K, Chen S, Du Z

Methods Ethical statement All animal experiments were approved by the Institutional Animal Care and Use Committee (IACUC) of The First Hospital of Jilin University

The installation and development of these diseases are closely linked to metabolic changes that generate a state of oxidative stress, due to the excessive production of reactive oxygen species (ROS) and reactive nitrogen species (RNS) [7,8]