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These results indicate that vincristine and DPI have an additive/synergistic interaction in MNA cells for reducing cell viability at low concentrations that are clinically achievable

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Core Mechanisms Recap: NNMT Inhibition: Prevents NAD depletion, supporting energy production and metabolic flexibility

This work was funded by: TS (Baylor College of Medicine, U01-AI24290, P01-AI152999, NINR R01-NR013497, and NIDDK P30-DK56338), SJW (NIDDK 1R41DK119052-01 and NIA P30-AG024832 [PI: E

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