herxing from glutathione system enhancement for cardiac protection: pharmacological options against oxidative stress and ferroptosis Fear of a Herxheimer Reaction
Description
Winnebeck, E

22, 25 Superoxide also leads to BH 4 oxidation (in fact, BH 4 is highly sensitive to oxidation), which promotes eNOS uncoupling and further ROS production

Gene 850:146917

doi: 10.1124/mol.115.098509 82 DupinN.LecuyerH.CarlottiA.PoyartC.CoureuilM.ChanalJ.et al

While glutathione is generally safe, its essential to consult with a healthcare provider if you are taking other medications, especially those that may affect liver function
Hypertensive crisis is a risk with the use of MAOIs
