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J Exp Med (2011) 208(11):232133

Whereas in the T state its main chain amide group hydrogen bonds to the carbonyl oxygen of Tyr A19 , the side chain can adopt different orientations (Figure 8)

Aliment Pharmacol Ther 14:639650

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doi: 10.1210/jcem-50-1-15

While there is a common misconception that methylcobalamin is vastly superior in initial gut absorptionpharmacokinetic studies suggest cyanocobalamin may absorb slightly better across the intestinal wall, but the true advantage of methylcobalamin lies in its cellular retention
