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These tight junction proteins permit the paracellular movement of molecules via two different pathways, which have been named the pore or leak pathway

Hou TT, Yang HY, Wang W, Wu QQ, Tian YR, Jia JP

ACG Clinical Guideline for the Diagnosis and Management of Gastroesophageal Reflux Disease [Review of ACG Clinical Guideline for the Diagnosis and Management of Gastroesophageal Reflux Disease]

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These results also indicated that these enzymes participated in different stages of M1 metabolizing BaP, causing a gradual BaP oxidation
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