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The amino-terminal ER-luminal segments of STIM proteins are the Ca 2+ sensing domains by virtue of specific EF-hand domain Ca 2+ binding sites,which are highly tuned to detect small changes in luminal Ca 2+ levels

Glutamine deprivation impairs function of infiltrating CD8+ T cells in hepatocellular carcinoma by inducing mitochondrial damage and apoptosis

Landi F, Calvani R, Tosato M, Martone AM, Ortolani E, Savera G, et al

The murine models were induced with myocardial infarction, and a cohort of the models was exposed to Semax in an experimental group for the following 6 days

The result is a peptide that retains structural integrity in environments, gastric fluid, intestinal lumen, serum, where conventional peptides are inactivated within minutes