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(2025), in Diabetes, Obesity and Metabolism, reported a weighted mean difference of 1.02 kg in lean body mass across 19 RCTs

These findings support semaglutide 2.4 mg as an effective therapeutic option for weight and fat mass reduction while preserving, or potentially improving, muscle function and metabolic health

males: SD vs WD: p = 0.000, Cohens d = 4.331
They are a function of the medication itself

[DOI] [PMC free article] [PubMed] [Google Scholar] 107.Gudbergsen H., Henriksen M., Whrens E.E., Overgaard A., Bliddal H., Christensen R., Boesen M.P., Knop F.K.K., Astrup A., Rasmussen M.U., et al

These behaviors often center around food-related problems, like searching for and saving food, acting on impulse, and repeatedly asking for food
