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Whilst it has a good safety profile, adverse effects of valproic acid in chronic use include hepatotoxicity ranging from transient elevation of liver enzymes to fulminant liver failure and hyperammonaemia with resultant encephalopathy

Qiao, Y., Li, M., Booth, R

Lokrantz and coworkers [72] recently reported the case of an old woman taking VPA monotherapy for her partial epilepsy in whom a typical hyperammonaemic encephalopathy was precipitated by treatment for a urinary tract infection with pivmecillinam an antibiotic known to decrease the serum concentration of carnitine

Powell Richard Powers Adam J

Dorr (April 2006)

[R] One of the more recently elucidated mechanisms by which it works that bodybuilders find most compelling is its effect on androgen receptor density in the muscle