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When the oxidative stress state persists and the damage progresses, senescent cells enter a senescent state marked by p16 upregulation, which consequently inhibits the kinases CDK4 and CDK6, thereby maintaining the stagnant state of the cell cycle [133, 134]

the value of combining multiple plant antioxidants to address different aspects of this heterogeneous syndrome

1997 Dec;138(12):5144-52

National Library of Medicine, NIH

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The benefits and risks of Gln supplementation in various diseases still need more data from clinical trials
