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Therapeutic potential of L-carnitine in coronary artery disease: a systematic review

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Additionally, higher levels of gut bacteria expressing CutC, the enzyme responsible for generating trimethylamine, correlated with longer survival in PDAC patients and enhanced responses to anti-PD1 immunotherapy in melanoma patients (238)

In addition, when circulating L-carnitine concentration increases, as in the case of oral supplementation, renal reabsorption of L-carnitine may become saturated, resulting in increased urinary excretion of L-carnitine (5)

Moeinian M, Ghasemi-Niri SF, Mozaffari S, Abdollahi M