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When GDH1 is downregulated, intracellular cysteine is diminished due to disruption of the cystine-glutamate transporter resulting from decreased SLC3A2 expression
BCRPs structure, substrate selectivity, and localization in the placenta suggest that, like P-gp, they could exert a protective role in removing cytotoxic drugs or chemicals from the fetus [92,93]
Molecular pathogenesis of pulmonary arterial hypertension
Here, a comparative study of the ability of MG detoxification of these three enzymes has been done in both E
T., Hamm, R
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