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Description
Rath et al., 2017, 2019)

Naturally produced by the body and found abundantly in heart muscle and skeletal tissue, L-carnitine functions mainly as a shuttle for fatty acids, transporting them into mitochondria, where theyre used for cellular energy production

Barrett JS, Gibson PR

SPARC plays a critical role in maintaining bone mass and quality [23]

Further investigations into carnitine and MAD may inform clinical decisions on carnitine supplementation to maximize the efficacy of MAD therapy

However, translating these results to the human situation in SBMA patients has its limitations and is far from a complete cure of SBMA patients (97, 98)