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Rath et al., 2017, 2019)

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Naturally produced by the body and found abundantly in heart muscle and skeletal tissue, L-carnitine functions mainly as a shuttle for fatty acids, transporting them into mitochondria, where theyre used for cellular energy production

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Barrett JS, Gibson PR

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SPARC plays a critical role in maintaining bone mass and quality [23]

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Further investigations into carnitine and MAD may inform clinical decisions on carnitine supplementation to maximize the efficacy of MAD therapy

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However, translating these results to the human situation in SBMA patients has its limitations and is far from a complete cure of SBMA patients (97, 98)

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