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This isn't a "push through" situation

Pharmacy Times, 73(4), 34-35

- If taking medications indicated for control of AD symptoms, on stable doses for at least 8 weeks prior to screening Exclusion criteria - Any history of bipolar affective disorder - A medical condition, other than AD, that may contribute to the individuals cognitive impairment - Stroke or transient ischemic attack in the past 12 months - Clinically significant unstable psychiatric condition in the past 6 months - Inability to swallow oral medications - Other medical conditions which the investigator deems would limit the individuals life expectancy to less than 6 months - Concurrent use of anti-depressant medication - Participation in another interventional clinical trial, or intake of another investigations drug within 4 weeks or 5 half-lives (whichever is longer) Study Estimands Primary estimand 1

doi: 10.1186/s10020-020-00234-7

When levels are low, the condition of dwarfism can develop
