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doi: 10.1016/j.etap.2010.10.009 52 HaapasaloH.KylniemiM.PaunulN.KinnulaV

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Substantial evidence indicates that mutations in several PD-associated genes (e.g., LRRK2, GBA, PINK1, PRKN, *DJ-1*) and the expression of risk alleles such as APOE4 exert their pathological effects by disrupting autophagy-related pathways, notably the autophagy-lysosomal pathway and mitophagy (3)

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Unilateral thalamic deep brain stimulation for refractory essential tremor and Parkinson's disease tremor

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Moreover, when we quantified SDSsoluble A and SDSinsoluble A separately (Fig 4CF), we found that SDSinsoluble A reduced after peptide treatment whereas SDSsoluble A increased

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Pathological hallmarks such as -synuclein (-syn) misfolding and Lewy body (LB) formation, along with mitochondrial dysfunction, oxidative stress, and neuroinflammation, further exacerbate neurodegeneration and neurotransmitter imbalances

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Aged garlic extract, a modulator of cardiovascular risk factors: a dose-finding study on the effects of AGE on platelet functions

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