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For example, to reduce immunogenicity of therapeutic mouse monoclonal antibodies, either the mouse Fc fragment or the whole antibody constant regions (CH1CH3) were replaced with the human counterparts by means of genetic manipulations, whereas the mouse Fab or Fv (VH-VL) fragments retained the original epitope specificity

Pickart, credited with discovering GHK-CU: No issues (involving GHK-Cu) have ever arisen during its use as a skin cosmetic or in human wound healing studies [2]

beta-Arrestin mediates the Frank-Starling mechanism of cardiac contractility

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