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2022;11:1724, Gern OL, Pavlou A, Mulenge F, Busker LM, Ghita L, Aringo A, et al

The gastrointestinal tract contains a significant portion of the immune system, and when gut integrity becomes compromised, inflammatory signaling can increase throughout the body

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First, the recognition that the gut microbiome is an essential determinant of neural, immune, and endocrine homeostasis: It is interesting to note that reasonably influential reviews of the ENS from 10 years ago that recognized the interactions between the cellular elements of the ENS in the control of intestinal homeostasis did not mention the gut microbiome (29, 136, 267, 329)

This protection extends to endothelial cells, where BPC-157 maintains vascular integrity during injury and supports endothelial function essential for tissue repair

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