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Early increments in H 2 O 2 levels and/or redox potential values were detected after 1 h of treatment, which could cause rapid induction of GSTs , GPXL6, and oxidative stress-induced genes, such as ANAC032 , AKR4C9 , HSFA8 , and OXI1 in 100 M SA-treated roots (Figs

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The role of exercise in the treatment plan is crucial, and numerous studies show that the best results are obtained after 1224 weeks, and clinical data support the need to continue these combined interventions consistently for at least 8 weeks (114)

Hence, the downstream pathways are targeted for drug development