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For the conventional phospholipids, the area under the curves were summed from positive ion-mode, for PIMs and MPMs negative ion-mode was used as these lipids were not quantifiable in positive ion-mode

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46 APAP can freely cross the selective maternal-fetal barrier of the placenta, after which it can then be metabolized by fetal hepatocytes, causing fetal hepatic necrosis if appropriate therapy with NAC is not administered in a timely manner

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616 , 617 Caring for people with dementia who have four or more behavioral and psychological symptoms (for example, aggression, selfharm and wandering) represents a tipping point, as these caregivers are more likely to report clinically meaningful depression and burden