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In many cases they possess an N-terminal signal peptide mediating correct subcellular sorting and trafficking and an anionic propeptide which is thought to be the major contributing factor inhibiting the antimicrobial activity by neutralizing the net positive charge of the mature peptide [19, 20]
24-hr human stool contains only about 5 g of cobalamin but about 100 g of apparent analogue (and 200 g of folate)
10.1523/JNEUROSCI.0181-11.2011 [DOI] [PMC free article] [PubMed] [Google Scholar] Nagoshi N., Tsuji O., Kitamura K., Suda K., Maeda T., Yato Y., et al
Appetite Regulation: Slows down stomach emptying, leading to increased feelings of fullness and reduced food intake
Haldar K, Mohandas N
doi: 10.1038/nature14407
