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The reason for this precaution is a) the lack of data on KD use in MCAD-deficient patients, and b) the fact that these patients respond well to glucose-based metabolism

B.ValentinoA.MargarucciS.GalderisiU.GiordanoA.PelusoG

This result has been confirmed by microbiota transplantation experiment

Patologicheskaia Fiziologiia i Eksperimental'naia Terapiia

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Two bi-functional proteins (DBP and LBP (dicarboxylic acids only)), which may contain cis -3, trans -2-enoyl-CoA epimerases, carry out the next two steps of hydration (enoyl-CoA hydratase) then dehydrogenation (hydroxyacyl-CoA dehydrogenase) to yield 3-keto intermediates