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Epitalon's primary mechanisms of action include: Telomere lengthening: Epitalon activates telomerase, the enzyme responsible for maintaining and rebuilding telomeres the protective caps on the ends of chromosomes

Drug Targets 21 , 884900 (2022)

Inhibitory effect of the synthetic pineal peptide epitalon on colon carcinogenesis induced by 1,2-dimethylhydrazine in rats

Grimm, A

Abstract Drugs may be given by a variety of routes

Because APAP-induced liver injury and recovery is regulated by an intricate system of intra- and extracellular molecular signaling, we here aim to quantify the importance of specific modules in determining the outcome after an APAP insult and of potential targets for therapies that mitigate adversity