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Metformin has been associated with reduced vitamin B12 absorption through effects on calcium-dependent membrane action in the terminal ileum, which may be relevant for patients on chronic metformin therapy

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In the per-protocol population (n = 120), the ln ratio in PWT was 0.267 for the cilostazol + L-carnitine treatment group versus 0.145 for the cilostazol + placebo treatment group (p = 0.048)

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10.1073/pnas.1216100110 Proc Natl Acad Sci

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