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Substrates of antioxidant enzymes, such as NAC, have demonstrated good therapeutic effects in the treatment of various diseases

In hyperglycemia, increased glycolytic flux leads to an abundance of pyruvate entering the tricarboxylic acid (TCA) cycle, generating excess NADH and FADH 2 , which further supply electrons to the ETC and exacerbate the reduced state of its components

doi: 10.3389/fonc.2012.00200 Received 30 August 2012 Accepted 07 December 2012 Published 26 December 2012 Volume 2 - 2012 Edited by Lorenzo Galluzzi, Institut National de la Sant et de la Recherche Medicale, France Reviewed by Patrizia Agostinis, Catholic University of Leuven, Belgium

doi: 10.1016/s0015-0282(02)03105-9

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Possible side effects include: Mild redness at the injection site Temporary swelling Minor tenderness Mild bruising Temporary irritation If you notice unexpected symptoms or have concerns during treatment, contact your healthcare provider as soon as possible