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Skin regeneration + wrinkle formation

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The discrepancies between both studies could be due, at least in part, to the different anatomic injection site employed, since, as indicated above, thigh injections have been rated more painful than injections in the abdomen [25, 26]

Liu, and J

With equal low affinity and no selectivity, each neurotrophins can bind to the pan-neurotrophin receptor p75 (p75NTR), and with high affinity to the tropomyosin-related kinase (Trk) receptor family: with NGF binding to TrkA, BDNF and NT4/5 to TrkB and NT3 to TrkC