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Description
10.23751/pn.v22i4.10460

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Generally, antibodies are categorized into those that target all lactylation modifications, such as Pan-Kla, and those that target specific sites, such as anti-H3K18la
Blood 120, 2012

L., Wang, L., Ramirez, L., Gamelli, R

Epidemiology: High levels of vitamin B12 were found in: Causes: Excessive supplementation (a direct increase in plasma vitamin B12 by excess intake or administration) Increased release of vitamin B12 from tissue stores (liberation from an internal reservoir): Solid tumors (especially hepatic or hematologic malignancies) Liver metastases Increased binding proteins: 7 Excess production: Liver disease (e.g., hepatitis, cirrhosis, hepatocellular carcinoma) damaged hepatocytes release haptocorrin (transcobalamin I) and B12 into circulation Myeloproliferative disorders these increase granulocyte production, which leads to more haptocorrin (transcobalamin I/III), a B12-binding protein produced by proliferating myeloid cells
