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Excessive Fe 2+ can react with lipid radicals and H 2 O 2 to produce a large amount of reactive oxygen species (ROS), which can damage membrane lipids, proteins, DNA, and other biological macromolecules, causing ferroptosis ( 3.2 Glutathione metabolism and ferroptosis GPX4 is an antioxidant enzyme found in mammalian cells

Berberich, A

Supplementary material The Supplementary Material for this article can be found online at: References 1 CalvaniR.PiccaA.LandiG.MariniF.BiancolilloA.Coelho-JuniorH

(PubMed) Boeke CE, Gillman MW, Hughes MD, Rifas-Shiman SL, Villamor E, Oken E

It is the opposite: a clear look at what people are talking about, what is actually known, and why competitive athletes should be careful

Hfe is the gene mutated in the most prevalent form of hereditary hemochromatosis