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Nitrosamines or their precursors occur in a wide variety of foods and manufactured and natural products, such as agricultural chemicals, tobacco, detergents, rust inhibitors, cutting fluids, rubber additives, solvents, drugs, plastics, tanned leather products, textiles, and cosmetics (ATSDR 1989a)

It is vulnerable to an oxidative stress induced injury due to the generation of reactive oxygen metabolites during the course of the alcohol metabolism and because of this, Alcoholic Liver Disease (ALD) has become a major cause of morbidity and mortality in India [23]

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In contrast, in laboratory studies it is easier to determine daily doses of EDCs where circumstances and most importantly the EDCs induction protocols are adequately controlled

In turn, eryptosis assays can be used to identify specific signaling pathways triggered by nanomaterials, which might shed light on their possible therapeutic application during in vitro toxicity testing