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Carnitine replacement in end-stage renal disease and hemodialysis
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Because there is no promising diseasemodifying medication for DPN, the pain itself needs to be managed when treating painful DPN
When the energy demand is high, inhibition of the isoform ACC2 of acetyl-CoA carboxylase increases fatty acid oxidation, while inhibition of the isoform ACC1 decreases fatty acid synthesis
Get professional advice if you think you might need an L-carnitine supplement or are already taking one to ensure you're not exceeding the amounts you may need.
