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Additionally, lipid metabolism decreases as the severity of the disease progresses (Zhao et al

showed the possible role of nuclear GSTpi in the acquisition of resistance to anticancer drugs by cancer cells (66, 67), it is unclear how GSTP translocated from the cytoplasm to nucleus and if in the macrophage, cytosolic GSTP could also enter into the nucleus

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In pathology, downregulation of ezrin expression is typically associated withand probably contributes toastrocytic atrophy, reduced number and volume of astrocytic leaflets, leaflet retraction and decreased synaptic coverage
